Renatrel, particularly its active stereoisomer levonorgestrel, operates by binding to progesterone and estrogen receptors located in various parts of the female reproductive system, including the reproductive tract, mammary gland, hypothalamus, and pituitary gland. Upon binding to these receptors, progestins like levonorgestrel decrease the frequency of gonadotropin-releasing hormone (GnRH) release from the hypothalamus and dampen the pre-ovulatory surge of luteinizing hormone (LH). The suppression of the LH surge effectively inhibits ovulation, thereby preventing pregnancy.
🛒 How to order this item?
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Show More
Renatrel (and more specifically the active stereoisomer levonorgestrel) binds to the progesterone and estrogen receptors within the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins like levonorgestrel will slow the frequency of release of gonadotropin-releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge. Loss of the LH surge inhibits ovulation and thereby prevents pregnancy.
It's recommended to avoid consuming alcohol while taking Renatrel to prevent potential adverse effects or interactions.
Renatrel is considered unsafe during pregnancy
Caution should be exercised during breastfeeding. It's advisable to consult a doctor before using this medication in such situations.
Renatrel is unlikely to affect the ability to drive or operate machinery when prescribed. However, individual responses may vary, so it's essential to follow medical advice.
There is insufficient information available regarding the use of Renatrel in patients with kidney dysfunction. Consulting a doctor is recommended in such cases to assess the suitability and safety of the medication.
There is insufficient information available regarding the use of Renatrel in patients with liver or kidney dysfunction.
Norgestrel is a progestin (female hormones). It works to prevent pregnancy by temporarily stopping the release of an egg from the ovary, or preventing fertilization (union) of the egg by sperm. It may also alter the lining of the uterus (womb) to stop a fertilized egg from attaching to the uterus.
Edema, Weakness, Anorexia, Amenorrhea, Breakthrough bleeding, Change in menstrual flow, Spotting
Renatrel, when combined with ethinyl estradiol, is primarily utilized for preventing pregnancy in women who choose this method of contraception. Additionally, Renatrel is employed in the treatment of various conditions, including:
Progestin-only oral contraceptives, like Norgestrel tablets, work by several mechanisms to prevent conception:
Suppression of ovulation: Progestins inhibit the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus, which in turn decreases the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. This suppression of LH and FSH prevents the maturation and release of an egg from the ovary, thus inhibiting ovulation.
Thickening of cervical mucus: Progestins thicken the cervical mucus, making it more difficult for sperm to penetrate into the uterus and reach the egg for fertilization.
Alteration of the endometrium: Progestins alter the lining of the uterus (endometrium), making it less favorable for implantation of a fertilized egg.
Lowering midcycle LH and FSH peaks: By reducing the levels of LH and FSH, progestins help to maintain a state of hormonal suppression, further inhibiting ovulation and pregnancy.
Slowing movement of the ovum: Progestins slow down the movement of the egg through the fallopian tubes, reducing the likelihood of fertilization by sperm.
After oral administration, serum levels of progestins peak about two hours later, followed by rapid distribution and elimination from the body. Within 24 hours after ingestion, serum levels return to near baseline, highlighting the importance of strict adherence to the dosing schedule for efficacy.
Contraception Monotherapy:
Monophasic Combined Oral Contraceptive (COC):
Triphasic COC:
Emergency Contraception:
Menopausal Hormone Replacement Therapy (HRT) as a progestogenic component:
Food Interaction:
Alcohol Interaction:
Cholesterol Interaction:
Hypertension Interaction:
Unknown Drug Interactions:
Disease Interactions:
Contraindicated in pregnancy (Category X) and considered unsafe during lactation
Store in a cool and dry place.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.